Nutritional Markers, Acute Phase Reactants and Tissue Inhibitor of Matrix Metalloproteinase 1 in Elderly Patients with Pressure Sores

Abstract

The general increase in acute-phase reactants observed in the elderly could be related to the intercurrent diseases. The generally low serum albumin level, lowest in patients with pressure sores, may be considered evidence of protein malnutrition and hypercatabolism. Regarding the morbidity, the increase in TIMP-1 levels could be explained as an adaptive process to prevent intrinsic protein expenditure of extracellular matrices.