Concepedia

A fluorinated analog of ISO-1 blocks the recognition and biological function of MIF and is orally efficacious in a murine model of colitis

Nilesh M. Dagia, Divya Kamath, Pooja Bhatt, Ravindra D. Gupte, Shruta S. Dadarkar, Lyle C. Fonseca, Gautam Agarwal, Anshu Chetrapal-Kunwar, Sarala Balachandran, Shaila Srinivasan,

European Journal of Pharmacology · 2009 · 34 citations · 33 references

DOI

Concepts

References

33

Improved protein–ligand docking using GOLD

Marcel L. Verdonk, Jason C. Cole, Michael J. Hartshorn et al. · Proteins Structure Function and Bioinformatics · 2003 · 3K citations · Full text

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MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment

Jürgen Bernhagen, Regina M. Krohn, Hongqi Lue et al. · Nature Medicine · 2007 · 1.3K citations

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DarT: The embryo test with the Zebrafish Danio rerio--a general model in ecotoxicology and toxicology.

Roland Nagel · PubMed · 2002 · 521 citations

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Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor.

Hong‐Wei Sun, Jürgen Bernhagen, Richard Bucala et al. · Proceedings of the National Academy of Sciences · 1996 · 331 citations

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ISO-1 Binding to the Tautomerase Active Site of MIF Inhibits Its Pro-inflammatory Activity and Increases Survival in Severe Sepsis

Yousef Al‐Abed, Darrin Dabideen, Bayan Aljabari et al. · Journal of Biological Chemistry · 2005 · 313 citations · Full text

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