Response to hydrocodone, codeine and oxycodone in a CYP2D6 poor metabolizer

Codeine Intoxication Associated with Ultrarapid CYP2D6 Metabolism

Yvan Gasche, Youssef Daali, Marc Fathi et al. · New England Journal of Medicine · 2004 · 700 citations · Full text

Medicine, Pharmacology, Toxicology +17

The CYP2D6 Poor Metabolizer Phenotype May Be Associated With Risperidone Adverse Drug Reactions and Discontinuation

José de León, Margaret T. Susce, Run-Mei Pan et al. · The Journal of Clinical Psychiatry · 2005 · 321 citations

Medicine, Pharmacokinetics, Pharmacology +16

Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation

Klaus Eckhardt, Shuxia Li, Susanne Ammon et al. · Pain · 1998 · 262 citations

Medicine, Pharmacology, Clinical Pharmacology +16

Inhibition by fluoxetine of cytochrome P450 2D6 activity

S V Otton, Dafang Wu, Russell T. Joffe et al. · Clinical Pharmacology & Therapeutics · 1993 · 260 citations

Medicine, Pharmacology, Pharmacotherapy +17

Mu receptor binding of some commonly used opioids and their metabolites

Zhao Rong Chen, Rodney J. Irvine, Andrew A. Somogyi et al. · Life Sciences · 1991 · 256 citations

Medicine, Medicinal Chemistry, Pharmacology +12