Overexpression of hepatitis B virus surface antigens including the preS1 region in a serum-free Chinese hamster ovary cell line

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

G Urlaub, Lawrence A. Chasin · Proceedings of the National Academy of Sciences · 1980 · 910 citations

Life Sciences, Genetics, Molecular Genetics +9

Large surface proteins of hepatitis B virus containing the pre-s sequence

K.‐H. Heermann, U Goldmann, W Schwartz et al. · Journal of Virology · 1984 · 820 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Human hepatitis B vaccine from recombinant yeast

W. J. McAleer, Eugene B. Buynak, Robert Z. Maigetter et al. · Nature · 1984 · 735 citations

Life Sciences, Biotechnology, Infectious Diseases +14

A controlled clinical trial of the efficacy of the hepatitis B vaccine (heptavax B): A final report

W. Szmuness, Cladd E. Stevens, Edith Zang et al. · Hepatology · 1981 · 464 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes.

Randal J. Kaufman, Peter C. Brown, Robert Schimke · Proceedings of the National Academy of Sciences · 1979 · 398 citations · Full text

Life Sciences, Genetics, Molecular Genetics +11