Publication | Closed Access
Growth hormone‐induced t cell differentiation
15
Citations
8
References
1973
Year
Human GrowthLymphocyte DevelopmentImmunologyImmune RegulationNormal ThymocytesCell TransplantationThymus BiologyCell SignalingRegulatory T Cell BiologyHelper FunctionAllergyGrowth HormoneHumoral ImmunityT Cell ImmunityEndocrinologyCell BiologyT Cell DifferentiationMedicineCell Development
Abstract Lymphoid cell suspensions were transferred into normal or thymectomized suckling mice and the recipients treated with growth hormone. After immunization, the number of antibody‐forming cells was counted in the spleens of recipients. Growth hormone was able to enhance the helper function of normal thymocytes, but not of lymph node and spleen cells or hydrocortisone‐resistant thymocytes. It is concluded that growth hormone induces T‐cell characteristics in thymocytes.
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