Proceedings of the National Academy of Sciences · 1993 · 186 citations · 2 references
Virus StructureBiophysical ModelingProtein FoldingMedicineNatural SciencesDiffusion ProcessNumerical MethodMolecular BiologyTobacco Mosaic VirusDiffusion CoefficientsProtein ModelingProtein Diffusion CoefficientsMicrobiologyProtein Phase SeparationDiffusion-based ModelingProteomicsBiophysicsComputational Biophysics
Diffusion coefficients for proteins in water are predicted. The numerical method developed is general enough to be applied to a wide range of protein surface shapes, from rodlike to globular. Results are presented for lysozyme and tobacco mosaic virus, and they are compared with actual data and with predictions made by less general methods.
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