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Quinazoline antifolates with dual biochemical loci of action. Biochemical and biological studies directed towards overcoming methotrexate resistance

Pharmaceutical ChemistryBiochemistryMedicinePharmacotherapyBiological StudiesDual Biochemical LociAntimicrobial ChemotherapyDrug DevelopmentPharmacologyMethotrexate ResistanceDrug DiscoveryDrug Resistance