Concepedia

A Phase II Study of the MDR Inhibitor Biricodar (INCEL, VX-710) and Paclitaxel in Women with Advanced Ovarian Cancer Refractory to Paclitaxel Therapy

Michael V. Seiden, Kenneth D. Swenerton, Ursula A. Matulonis, Susan Campos, Peter G. Rose, Gerald Batist, Ene Ette, Varun Garg, A. Fuller, Matthew W. Harding,

Gynecologic Oncology · 2002 · 98 citations · 40 references

DOI

Concepts

References

40

Cancer statistics, 1999

Sarah Landis, Thomas S. Murray, S. Bolden et al. · CA A Cancer Journal for Clinicians · 1999 · 3.1K citations · Full text

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Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

Preet M. Chaudhary, Igor B. Roninson · Cell · 1991 · 957 citations

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Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.

Kevin E. Noonan, Christian Beck, Tatyana A. Holzmayer et al. · Proceedings of the National Academy of Sciences · 1990 · 729 citations · Full text

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Paclitaxel-resistant Human Ovarian Cancer Cells Have Mutant β-Tubulins That Exhibit Impaired Paclitaxel-driven Polymerization

Paraskevi Giannakakou, Dan L. Sackett, Yoon‐Koo Kang et al. · Journal of Biological Chemistry · 1997 · 682 citations · Full text

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Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes.

Maria Kavallaris, Dennis Yi‐Shin Kuo, Catherine A. Burkhart et al. · Journal of Clinical Investigation · 1997 · 599 citations · Full text

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