Concepedia

The Mode of Action of Taxol: Apoptosis at Low Concentration and Necrosis at High Concentration

T.K. Yeung, Colin Germond, Xinmei Chen, Zhixiang Wang

Biochemical and Biophysical Research Communications · 1999 · 159 citations · 23 references

DOI

Concepts

References

23

Promotion of microtubule assembly in vitro by taxol

Peter B. Schiff, Jane Fant, Susan Band Horwitz · Nature · 1979 · 3.6K citations

, , +9

Taxol stabilizes microtubules in mouse fibroblast cells.

Peter B. Schiff, S. B. Horwitz · Proceedings of the National Academy of Sciences · 1980 · 2K citations · Full text

, , +17

High-Resolution Model of the Microtubule

Eva Nogales, Michael Whittaker, Ronald A. Milligan et al. · Cell · 1999 · 1.2K citations · Full text

, , +12

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

Mary Ann Jordan, Robert Toso, Douglas Thrower et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations · Full text

, , +17

Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death.

M A Jordan, K Wendell, Sheila M. Gardiner et al. · PubMed · 1996 · 783 citations

, , +17