Concepedia

Uptake and efficacy of trimetrexate (TMQ, 2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl] quinazoline), a non-classical antifolate in methotrexate-resistant leukemia cells in vitro

Barton A. Kamen, Beatrice Eibl, Arlene R. Cashmore, Joseph Bertino

Biochemical Pharmacology · 1984 · 112 citations · 6 references

DOI

Concepts

References

6

Transport Energetics of the Folic Acid Analogue, Methotrexate, in L1210 Leukemia Cells

I. David Goldman · Journal of Biological Chemistry · 1969 · 131 citations · Full text

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A rapid, radiochemical-ligand binding assay for methotrexate

Barton A. Kamen, Patricia L. Takach, Radka Vatev et al. · Analytical Biochemistry · 1976 · 106 citations

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2,4-Diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline (TMQ), a potent non-classical folate antagonist inhibitor—I

Joseph R. Bertino, Wendy L. Sawicki, Barbara A. Moroson et al. · Biochemical Pharmacology · 1979 · 79 citations

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Pharmacology and toxicity of a potent "nonclassical" 2,4-diamino quinazoline folate antagonist, trimetrexate, in normal dogs.

Eleanor C. Weir, Arlene R. Cashmore, Robert N. Dreyer et al. · PubMed · 1982 · 33 citations

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Effect of [3H]methotrexate impurities on apparent transport of methotrexate by a sensitive and resistant L1210 cell line.

B A Kamen, Arlene R. Cashmore, Robert N. Dreyer et al. · Journal of Biological Chemistry · 1980 · 27 citations · Full text

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