Cancer Cell · 2009 · 123 citations · 38 references
Life SciencesCell BiologyOncologyApoptosisMolecular OncologyOncogenesApoptosis In CancerApoptosis RegulationApoptosis ResistanceApoptotic Signal TransductionApoptotic SignalingIntrinsic Apoptotic PathwayApoptosis Signaling In CancerApoptotic Signaling In CancerCancer Cell ApoptosisP53 InactivationP53 Pathway InactivationP53-mediated ApoptosisTumor Suppressor P53
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Bert Vogelstein, David P. Lane, Arnold J. Levine · Nature · 2000 · 6.6K citations
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
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Mdm2 promotes the rapid degradation of p53
Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations
Regulation of p53 stability by Mdm2
Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations
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Tobias Sjöblom, Siân Jones, Laura D. Wood et al. · Science · 2006 · 3.2K citations