Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

Regulation of Cell Survival by Secreted Proneurotrophins

Ramee Lee, Pouneh Kermani, Kenneth K. Teng et al. · Science · 2001 · 1.6K citations

ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75^NTRand Sortilin

Henry Teng, Kenneth K. Teng, Ramee Lee et al. · Journal of Neuroscience · 2005 · 982 citations · Full text

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

Kuo‐Fen Lee, En Li, L. Julie Huber et al. · Cell · 1992 · 959 citations

Neuropeptides, Systems Biology, Molecular Neuroscience +10

Sortilin is essential for proNGF-induced neuronal cell death

Ramee Lee, Kenneth K. Teng, Pernille Jansen et al. · Nature · 2004 · 935 citations

Autophagy, Cell Death, Neuroprotection +3

Variant Brain-Derived Neurotrophic Factor (BDNF) (Met66) Alters the Intracellular Trafficking and Activity-Dependent Secretion of Wild-Type BDNF in Neurosecretory Cells and Cortical Neurons

Zhe-Yu Chen, Paresh D. Patel, Gayatree Sant et al. · Journal of Neuroscience · 2004 · 871 citations · Full text

Bdnf Gene, Neurochemical Biomarkers, Synaptic Signaling +18