Concepedia

Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

Pernille Jansen, Klaus M. Giehl, Jens Randel Nyengaard, Kenneth K. Teng, Oleg Lioubinski, Susanne S. Sjoegaard, Tilman Breiderhoff, Michael Gotthardt, Fuyu Lin, Andreas Eilers,

Nature Neuroscience · 2007 · 275 citations · 46 references

DOI

Concepts

References

46

Regulation of Cell Survival by Secreted Proneurotrophins

Ramee Lee, Pouneh Kermani, Kenneth K. Teng et al. · Science · 2001 · 1.6K citations

, , +16

ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75<sup>NTR</sup>and Sortilin

Henry Teng, Kenneth K. Teng, Ramee Lee et al. · Journal of Neuroscience · 2005 · 993 citations · Full text

, , +17

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

Kuo‐Fen Lee, En Li, L. Julie Huber et al. · Cell · 1992 · 962 citations

, , +14

Sortilin is essential for proNGF-induced neuronal cell death

Ramee Lee, Kenneth K. Teng, Pernille Jansen et al. · Nature · 2004 · 944 citations

, , +12

Variant Brain-Derived Neurotrophic Factor (BDNF) (Met66) Alters the Intracellular Trafficking and Activity-Dependent Secretion of Wild-Type BDNF in Neurosecretory Cells and Cortical Neurons

Zhe-Yu Chen, Paresh D. Patel, Gayatree Sant et al. · Journal of Neuroscience · 2004 · 874 citations · Full text

, , +15