1‘-Benzyl-3,4-dihydrospiro[2<i>H</i>-1- benzothiopyran-2,4‘-piperidine] (Spipethiane), a Potent and Highly Selective σ₁ Ligand

Analysis of radioligand binding experiments

Grant A. McPherson · Journal of Pharmacological Methods · 1985 · 1.2K citations

Natural Sciences, Biochemistry, Chemistry +9

Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

Markus Hanner, Fabian F. Moebius, Astrid Flandorfer et al. · Proceedings of the National Academy of Sciences · 1996 · 908 citations

Medicine, Biochemistry, Pharmacology +13

Cloning and Functional Expression of the Human Type 1 Sigma Receptor (hSigmaR1)

Ramesh Kekuda, Puttur D. Prasad, You-Jun Fei et al. · Biochemical and Biophysical Research Communications · 1996 · 415 citations

Life Sciences, Genetics, Molecular Biology +5

A sigma-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from that of guinea pig brain

Susan B. Hellewell, W. Don Bowen · Brain Research · 1990 · 388 citations

Medicine, Neuroscience, Pharmacology +8

Characterization of the binding of [3H](+)-pentazocine to σ recognition sites in guinea pig brain

Diane L. DeHaven‐Hudkins, Lorraine C. Fleissner, Felicia Y. Ford-Rice · European Journal of Pharmacology Molecular Pharmacology · 1992 · 177 citations

Medicine, Neuroscience, Pharmacology +9