Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity

A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and Cytotoxicity

Dagmar Fischer, Thorsten Bieber, Youxin Li et al. · Pharmaceutical Research · 1999 · 1.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

Degradable Poly(β-amino esters):  Synthesis, Characterization, and Self-Assembly with Plasmid DNA

David M. Lynn, Róbert Langer · Journal of the American Chemical Society · 2000 · 913 citations

Natural Sciences, Biochemistry, Biotechnology +17

Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle

W.T. Godbey, Kenneth K. Wu, Antonios G. Mikos · Journal of Biomedical Materials Research · 1999 · 822 citations

Pharmacy, Bioengineering, Biotechnology +16

A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery

Jordan J. Green, Róbert Langer, Daniel G. Anderson · Accounts of Chemical Research · 2008 · 583 citations

Pharmacy, Biotechnology, Molecular Biology +17

Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery

David V. Schaffer, Nick A. Fidelman, Nily Dan et al. · Biotechnology and Bioengineering · 2000 · 521 citations

Pharmacy, Molecular Biology, Pharmaceutics +17