Concepedia

Polymer Toxicity

Polymer Toxicity is a biochemical property that characterizes the adverse effects of polymeric gene carriers on cellular viability and function due to their chemical composition, molecular weight, charge density, and degradation byproducts.

402

Publications

26K

Citations

1.8K

Authors

611

Institutions

Publications per year

2017–2026

105

Parents

Publications

402

In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis

Dagmar Fischer, Youxin Li, Barbara Ahlemeyer et al. · Biomaterials · 2003 · 2.3K citations

, , +16

A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy

S. Moein Moghimi, Peter Symonds, J. Clifford Murray et al. · Molecular Therapy · 2005 · 1.1K citations · Full text

, , +17

Cytotoxicity of thermosensitive polymers poly(N-isopropylacrylamide), poly(N-vinylcaprolactam) and amphiphilically modified poly(N-vinylcaprolactam)

Henna Vihola, Antti Laukkanen, Lauri Valtola et al. · Biomaterials · 2004 · 671 citations

, , +11

Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini

David Putnam, Christine Gentry, Daniel W. Pack et al. · Proceedings of the National Academy of Sciences · 2001 · 491 citations

, , +17

Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity

Arkadi Zintchenko, Alexander Philipp, Ali Dehshahri et al. · Bioconjugate Chemistry · 2008 · 466 citations · Full text

, , +17

1–5 of 402

Authors

1.8K

  1. MB
    Maria Bryszewska

    University of Łódź, Poland

    5 publications · 136 citations

    5

    h-index

  2. RM
    Raphael M. Ottenbrite

    Virginia Commonwealth University, United States

    5 publications · 120 citations

    5

    h-index

  3. RD
    Ruth Duncan

    Keele University, United Kingdom

    5 publications · 305 citations

    5

    h-index

  4. PF
    Paolo Ferruti

    University of Milan, Italy

    4 publications · 165 citations

    4

    h-index

  5. TK
    Thomas Kissel

    Philipps University of Marburg, Germany

    4 publications · 2.5K citations

    4

    h-index

1–5 of 1.8K

Institutions

611

  1. Massachusetts Institute of Technology

    Cambridge, United States

    9 h-index

    21 publications

    4K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    22 publications

    990 citations

  3. Virginia Commonwealth University

    Richmond, United States

    5 h-index

    5 publications

    120 citations

  4. Johannes Gutenberg University Mainz

    Mainz, Germany

    5 h-index

    17 publications

    322 citations

  5. Utrecht University

    Utrecht, The Netherlands

    5 h-index

    25 publications

    2.5K citations

  6. University of Łódź

    Lodz, Poland

    5 h-index

    13 publications

    373 citations

  7. University of Washington

    Seattle, United States

    5 h-index

    29 publications

    1.6K citations

  8. Kyoto University

    Kyoto, Japan

    5 h-index

    9 publications

    678 citations

1–8 of 611

Venues

  1. Biomacromolecules

    21 publications · 1.4K citations

    20

    h-index

  2. Biomaterials

    14 publications · 4.3K citations

    14

    h-index

  3. Macromolecular Bioscience

    11 publications · 687 citations

    11

    h-index

  4. PubMed

    Repository · 13 publications · 628 citations

    11

    h-index

  5. Toxicology and Applied Pharmacology

    TAAP · 10 publications · 375 citations

    10

    h-index

1–5