Chitosan as a nonviral gene delivery system. Structure–property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid

Joseph Zabner, A Fasbender, Tom Moninger et al. · Journal of Biological Chemistry · 1995 · 1.4K citations · Full text

Pharmacy, Biotechnology, Molecular Biology +16

Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations.

Jiin Felgner, Rajesh Kumar, Ch. Sridhar et al. · Journal of Biological Chemistry · 1994 · 1.3K citations · Full text

Pharmacy, Biochemistry, Pharmaceutics +17

A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and Cytotoxicity

Dagmar Fischer, Thorsten Bieber, Youxin Li et al. · Pharmaceutical Research · 1999 · 1.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

Oral gene delivery with chitosan–DNA nanoparticles generates immunologic protection in a murine model of peanut allergy

Krishnendu Roy, Hai‐Quan Mao, Shau Ku Huang et al. · Nature Medicine · 1999 · 1.1K citations

Life Sciences, Biotechnology, Immunology +17