Concepedia

GMP production and characterization of the bivalent anti-human T cell immunotoxin, A-dmDT390-bisFv(UCHT1) for phase I/II clinical trials

Jung Hee Woo, Jen-Sing Liu, Soo Hyun Kang, Ravibhushan Singh, Seong Kyu Park, Yunpeng Su, Janelle Ortiz, David M. Neville, Mark C. Willingham, Arthur E. Frankel

Protein Expression and Purification · 2007 · 23 citations · 22 references

DOI

Concepts

References

22

Tissue sulfhydryl groups

George L. Ellman · Archives of Biochemistry and Biophysics · 1959 · 26.2K citations

High resolution two-dimensional electrophoresis of proteins.

Patrick H. O’Farrell · Journal of Biological Chemistry · 1975 · 19.4K citations · Full text

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Pivotal Phase III Trial of Two Dose Levels of Denileukin Diftitox for the Treatment of Cutaneous T-Cell Lymphoma

Elise A. Olsen, Madeleine Duvic, Arthur E. Frankel et al. · Journal of Clinical Oncology · 2001 · 610 citations

, , +17

Phase I trial of a novel diphtheria toxin/granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia.

Arthur E. Frankel, Bayard L. Powell, Philip D. Hall et al. · PubMed · 2002 · 113 citations

, , +17

Gene optimization is necessary to express a bivalent anti-human anti-T cell immunotoxin in Pichia pastoris

Jung Hee Woo, Yuan Yi Liu, Askale Mathias et al. · Protein Expression and Purification · 2002 · 102 citations

, , +11