Zoledronic acid-induced IPP/ApppI production in vivo

Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure.

Masahiko Sato, W A Grasser, Naoto Endo et al. · Journal of Clinical Investigation · 1991 · 1K citations · Full text

Medicine, Endocrinology, Bone Augmentation +14

Clodronate and Liposome-Encapsulated Clodronate Are Metabolized to a Toxic ATP Analog, Adenosine 5′-(β,γ-Dichloromethylene) Triphosphate, by Mammalian Cells In Vitro

Julie C. Frith, Jukka Mönkkönen, G. Michael Blackburn et al. · Journal of Bone and Mineral Research · 1997 · 440 citations · Full text

Medicine, Pharmacology, Toxicology +12

Removal of Osteoclast Bone Resorption Products by Transcytosis

Jari Salo, Petri Lehenkari, Mika Mulari et al. · Science · 1997 · 433 citations

Medicine, Biochemistry, Cell Biology +16

Trafficking of Matrix Collagens Through Bone-Resorbing Osteoclasts

Stephen A. Nesbitt, Michael A. Horton · Science · 1997 · 375 citations

Medicine, Biochemistry, Cell Biology +17

Further Insight into Mechanism of Action of Clodronate: Inhibition of Mitochondrial ADP/ATP Translocase by a Nonhydrolyzable, Adenine-Containing Metabolite

Petri Lehenkari, Maarit Kellinsalmi, Juha Näpänkangas et al. · Molecular Pharmacology · 2002 · 328 citations

Medicine, Cell Biology, Pharmacology +17