Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.8K citations

Medicine, Oncology, Pharmacology +10

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

Mikuláš Popovič, M. G. Sarngadharan, Elizabeth J. Read et al. · Science · 1984 · 3.5K citations

Life Sciences, Immunology, Molecular Biology +17

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

Michael E. Greenberg, Edward B. Ziff · Nature · 1984 · 3.2K citations

Medicine, Genetics, Molecular Biology +11

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

Rudi Pauwels, Jan Balzarini, Masanori Baba et al. · Journal of Virological Methods · 1988 · 1.6K citations

Life Sciences, Infectious Diseases, Analytical Chemistry +12

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

Michael H. Malim, Joachim Hauber, Shu‐Yun Le et al. · Nature · 1989 · 1.3K citations

Life Sciences, Molecular Biology, Molecular Genetics +17