Antimicrobial properties of some erucic acid‐glycolic acid derivatives

Abstract

Abstracts Twelve fatty acid derivatives of glycolic acid containing erucic acid, or other selected vegetable oil fatty acids, were synthesized. These were screened for antimicrobial activity against a gram‐positive bacterium, Staphylococcus aureus ; a gram‐negative bacterium, Escherichia coli ; a mold, Penicillium notatum , and a yeast, Candida utilis. All of the compounds inhibited at least one of these organisms. These compounds were derivatives of glycolic acid prepared by esterification of the carboxyl function of glycolic acid with a long‐chain fatty alcohol and reaction of the hydroxyl function of glycolic acid with a long‐chain fatty acyl group.