Concepedia

New malaria vaccine candidates based on the Plasmodium vivax Merozoite Surface Protein-1 and the TLR-5 agonist Salmonella Typhimurium FliC flagellin

Daniel Y. Bargieri, Daniela Santoro Rosa, Catarina Joelma Magalhães Braga, Bruna O. Carvalho, Fábio Trindade Maranhão Costa, Noeli Maria Espíndola, Adelaide José Vaz, Irene S. Soares, Luís Carlos de Souza Ferreira, Maurício M. Rodrigues

Vaccine · 2008 · 132 citations · 60 references

DOI

Concepts

References

60

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages

Luigi Franchi, Amal O. Amer, Mathilde Body–Malapel et al. · Nature Immunology · 2006 · 1.1K citations

, , +16

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf

Edward A. Miao, Celia Alpuche‐Aranda, Monica Dors et al. · Nature Immunology · 2006 · 1.1K citations

, , +14

Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility

Kelly D. Smith, Erica Andersen‐Nissen, Fumitaka Hayashi et al. · Nature Immunology · 2003 · 813 citations

, , +14

A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.

Michael J. Blackman, H. G. Heidrich, Stuart P. Donachie et al. · The Journal of Experimental Medicine · 1990 · 560 citations · Full text

, , +15

Flagellin-Deficient Legionella Mutants Evade Caspase-1- and Naip5-Mediated Macrophage Immunity

Tao Ren, Dario S. Zamboni, Craig R. Roy et al. · PLoS Pathogens · 2006 · 535 citations · Full text

, , +17