Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene

Alexander Poltorak, Xiaolong He, Irina Smirnova, +11

Science

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp

Molecular Cell

Gout-associated uric acid crystals activate the NALP3 inflammasome

Fabio Martinon, Virginie Pétrilli, Annick Mayor, +2

Nature

InflammationNalp3 InflammasomeUrologyAnti-inflammatoryGouty Arthritis +5

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

Fumitaka Hayashi, Kelly D. Smith, Adrian Ozinsky, +7

Nature

Host ResponseToll-like ReceptorsBacterial FlagellinAutoimmune DiseaseVirulence Factor +9

Cryopyrin activates the inflammasome in response to toxins and ATP

Sanjeev Mariathasan, David S. Weiss, Kim Newton, +7

Nature

Cell PhysiologyReductive StressSignal TransductionBiochemistryNatural Sciences +9

Nod2 Is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection

Stephen E. Girardin, Ivo G. Boneca, Jérôme Viala, +5

Journal of Biological Chemistry

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

Sanjeev Mariathasan, Kim Newton, Denise M. Monack, +6

Nature

InflammationAnti-inflammatorySignal TransductionImmunologyChronic Inflammation +9

NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder

Laetitia Agostini, Fabio Martinon, Kimberly Burns, +3

Immunity

InflammationMuckle-wells Autoinflammatory DisorderIl-1β-processing InflammasomeImmunologyChronic Inflammation +10

Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2

Naohiro Inohara, Yasunori Ogura, Ana Fontalba, +11

Journal of Biological Chemistry

InflammationMolecular ImmunologyAntimicrobial Drug DiscoveryAutoimmune DiseaseMucosal Immunology +13

Nod1 Detects a Unique Muropeptide from Gram-Negative Bacterial Peptidoglycan

Stephen E. Girardin, Ivo G. Boneca, Letícia A. M. Carneiro, +12

Science