Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets

Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data

Clifford S. Patlak, Ronald G. Blasberg, Joseph D. Fenstermacher · Journal of Cerebral Blood Flow & Metabolism · 1983 · 3.6K citations · Full text

Engineering, Neurophysiological Biomarkers, Biomedical Engineering +23

The distribution of substance P and 5‐hydroxytryptamine in the central nervous system of the dog

T. B. B. Crawford, J. H. Gaddum · The Journal of Physiology · 1954 · 698 citations · Full text

Psychoactive Drug, Neurophysiology, Neuroanatomy +12

Pharmacological properties of a potent and selective nonpeptide substance P antagonist.

C. Garret, A. Carruette, V Fardin et al. · Proceedings of the National Academy of Sciences · 1991 · 429 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmacological Study +15

Pharmacology of CP-99,994; a nonpeptide antagonist of the tachykinin neurokinin-1 receptor.

Stafford McLean, Alan H. Ganong, P A Seymour et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 222 citations

Investigation into species variants in tachykinin NK₁ receptors by use of the non‐peptide antagonist, CP‐96,345

I.J.M. Beresford, P.J. Birch, R.M. Hagan et al. · British Journal of Pharmacology · 1991 · 220 citations · Full text