Concepedia

Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part I: Discovery of 3-(2-hydroxyethoxy)-4-methoxy-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide

Yoshikazu Uto, Tsuneaki Ogata, Jun Harada, Yohei Kiyotsuka, Yuko Ueno, Yuriko Miyazawa, Hitoshi Kurata, Tsuneo Deguchi, Nobuaki Watanabe, Toshiyuki Takagi,

Bioorganic & Medicinal Chemistry Letters · 2009 · 22 citations · 15 references

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Concepts

References

15

The Biosynthesis of Hepatic Cholesterol Esters and Triglycerides Is Impaired in Mice with a Disruption of the Gene for Stearoyl-CoA Desaturase 1

Makoto Miyazaki, Young‐Cheul Kim, Mark P. Gray-Keller et al. · Journal of Biological Chemistry · 2000 · 452 citations · Full text

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Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia

Alan Attie, Ronald M. Krauss, Mark P. Gray-Keller et al. · Journal of Lipid Research · 2002 · 348 citations · Full text

, , +16

Direct Organocatalytic Asymmetric α-Chlorination of Aldehydes

Nis Halland, Alan Braunton, Stephan Bachmann et al. · Journal of the American Chemical Society · 2004 · 328 citations

, , +11

Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites

Lin Zhang, Lan Ge, Satish Parimoo et al. · Biochemical Journal · 1999 · 238 citations · Full text

, , +17

Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates

Jian Wang, Yu Lan, Robert E. Schmidt et al. · Biochemical and Biophysical Research Communications · 2005 · 226 citations

, , +5