Yuriko Miyazawa

Metabolites of Febrifugine and Its Synthetic Analogue by Mouse Liver S9 and Their Antimalarial Activity against <i>Plasmodium</i> Malaria Parasite

Shingo Hirai, Haruhisa Kikuchi, Hye‐Sook Kim et al. · Journal of Medicinal Chemistry · 2003 · 71 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Synthesis and evaluation of novel stearoyl-CoA desaturase 1 inhibitors: 1′-{6-[5-(pyridin-3-ylmethyl)-1,3,4-oxadiazol-2-yl]pyridazin-3-yl}-3,4-dihydrospiro[chromene-2,4′-piperidine] analogs

Yoshikazu Uto, Yuko Ueno, Yohei Kiyotsuka et al. · European Journal of Medicinal Chemistry · 2010 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Novel spiropiperidine-based stearoyl-CoA desaturase-1 inhibitors: Identification of 1′-{6-[5-(pyridin-3-ylmethyl)-1,3,4-oxadiazol-2-yl]pyridazin-3-yl}-5-(trifluoromethyl)-3,4-dihydrospiro[chromene-2,4′-piperidine]

Yoshikazu Uto, Yohei Kiyotsuka, Yuko Ueno et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide and its biological evaluation

Yoshikazu Uto, Tsuneaki Ogata, Yohei Kiyotsuka et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 28 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Novel benzoylpiperidine-based stearoyl-CoA desaturase-1 inhibitors: Identification of 6-[4-(2-methylbenzoyl)piperidin-1-yl]pyridazine-3-carboxylic acid (2-hydroxy-2-pyridin-3-ylethyl)amide and its plasma triglyceride-lowering effects in Zucker fatty rats

Yoshikazu Uto, Tsuneaki Ogata, Yohei Kiyotsuka et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 28 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16