Folic acid supplementation, MTHFR and MTRR polymorphisms, and the risk of childhood leukemia: the ESCALE study (SFCE)

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Bryan Howie, Peter Donnelly, Jonathan Marchini · PLoS Genetics · 2009 · 4.1K citations · Full text

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Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage

Benjamin C. Blount, M. M. Mack, Carol M. Wehr et al. · Proceedings of the National Academy of Sciences · 1997 · 1.4K citations

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A Second Genetic Polymorphism in Methylenetetrahydrofolate Reductase (MTHFR) Associated with Decreased Enzyme Activity

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A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status

Simonetta Friso, Sang‐Woon Choi, Domenico Girelli et al. · Proceedings of the National Academy of Sciences · 2002 · 931 citations

Medicine, Genetics, Molecular Genetics +17

The 1298A→C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine

Inbal Weisberg · Atherosclerosis · 2001 · 367 citations

Life Sciences, Genetics, Molecular Genetics +9