Sang‐Woon Choi

A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status

Simonetta Friso, Sang‐Woon Choi, Domenico Girelli et al. · Proceedings of the National Academy of Sciences · 2002 · 931 citations

Medicine, Genetics, Molecular Genetics +17

Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene.

Lori Stern, JB Mason, Jacob Selhub et al. · PubMed · 2000 · 392 citations

Life Sciences, Genetics, Molecular Genetics +15

DNA Methylation Changes after 5-Aza-2′-Deoxycytidine Therapy in Patients with Leukemia

Allen S. Yang, Ketan D. Doshi, Sang‐Woon Choi et al. · Cancer Research · 2006 · 268 citations

Medicine, Molecular Biology, Oncology +15

A Method to Assess Genomic DNA Methylation Using High-Performance Liquid Chromatography/Electrospray Ionization Mass Spectrometry

Simonetta Friso, Sang‐Woon Choi, Gregory G. Dolnikowski et al. · Analytical Chemistry · 2002 · 233 citations

Life Sciences, Biochemistry, Molecular Biology +17

Dietary folate protects against the development of macroscopic colonic neoplasia in a dose responsive manner in rats.

Young-In Kim, Robert Salomon, Fiona Graeme‐Cook et al. · Gut · 1996 · 193 citations · Full text

Medicine, Nutritional Sciences, Oncology +9