Arecoline and the 30–100 kDa fraction of areca nut extract differentially regulate mTOR and respectively induce apoptosis and autophagy: a pilot study

Inhibition of Mammalian Target of Rapamycin or Apoptotic Pathway Induces Autophagy and Radiosensitizes PTEN Null Prostate Cancer Cells

Carolyn Cao, Ty K. Subhawong, Jeffrey M. Albert et al. · Cancer Research · 2006 · 332 citations · Full text

Medicine, Oncology, Pharmacology +17

Independent and combined effects of alcohol intake, tobacco smoking and betel quid chewing on the risk of esophageal cancer in Taiwan

Chien‐Hung Lee, Jang‐Ming Lee, Deng‐Chyang Wu et al. · International Journal of Cancer · 2004 · 238 citations

Medicine, Oncology, Cancer Epidemiology +13

Increased autophagy in transgenic mice with a G93A mutant SOD1 gene

Nobutoshi Morimoto, Makiko Nagai, Yasuyuki Ohta et al. · Brain Research · 2007 · 221 citations

Life Sciences, Genetics, Molecular Biology +12

Dopamine induces autophagic cell death and α‐synuclein increase in human neuroblastoma SH‐SY5Y cells

Cristina Gómez-Santos, Isidró Ferrer, Antonio F. Santidrián et al. · Journal of Neuroscience Research · 2003 · 187 citations

Life Sciences, Neurobiology, Neuroscience +17

Areca nut extract and arecoline induced the cell cycle arrest but not apoptosis of cultured oral KB epithelial cells: association of glutathione, reactive oxygen species and mitochondrial membrane potential

Mei‐Chi Chang · Carcinogenesis · 2001 · 168 citations · Full text

Medicine, Oral Biology, Pharmacology +15