Concepedia

Zedoarondiol isolated from the rhizoma of Curcuma heyneana is involved in the inhibition of iNOS, COX-2 and pro-inflammatory cytokines via the downregulation of NF-κB pathway in LPS-stimulated murine macrophages

Woong Cho, Joo‐Won Nam, HyunJun Kang, Tri Windono, Eun‐Kyoung Seo, Kyung‐Tae Lee

International Immunopharmacology · 2009 · 99 citations · 32 references

DOI

Concepts

References

32

A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells

Jiahuai Han, Jeffrey Lee, L. Bibbs et al. · Science · 1994 · 2.7K citations

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

, , +6

Nitric oxide and superoxide in inflammation and immune regulation.

Tomasz J. Guzik, Ryszard Korbut, T Adamek-Guzik · PubMed · 2003 · 1.1K citations

, , +16

Site-Specific Phosphorylation of IκBα by a Novel Ubiquitination-Dependent Protein Kinase Activity

Zhijian J. Chen, Lana Parent, Tom Maniatis · Cell · 1996 · 955 citations · Full text

, , +11

p38 and Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase Pathways Are Required for Nuclear Factor-κB p65 Transactivation Mediated by Tumor Necrosis Factor

Wim Vanden Berghe, Stéphane Plaisance, Elke Boone et al. · Journal of Biological Chemistry · 1998 · 681 citations · Full text