Concepedia

Publication | Open Access

Granulocyte Colony-Stimulating Factor (G-CSF) Protects Oligpdendrocyte and Promotes Hindlimb Functional Recovery after Spinal Cord Injury in Rats

DOIFull Paper Access

68

Citations

31

References

2012

Year

Ryo Kadota, Masao Koda, Junko Kawabe, Masayuki Hashimoto, Yutaka Nishio, Chikato Mannoji, Tomohiro Miyashita, Takeo Furuya, Akihiko Okawa, Kazuhisa Takahashi,
PLoS ONE

Abstract

G-CSF protects oligodendrocyte from SCI-induced cell death via the suppression of inflammatory cytokines and up-regulation of anti-apoptotic protein. As a result, G-CSF attenuates white matter loss and promotes hindlimb functional recovery.

References

YearCitations

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