Sensitization to acid‐hydrolyzed wheat protein by transdermal administration to <scp>BALB</scp>/c mice, and comparison with gluten

Abstract

Transdermal exposure to HWP1 is sufficient to activate key immune pathways necessary for sensitizing mice for immediate hypersensitivity reactions. This study shows that HWP has a sensitizing potential as well as gluten, whereas its allergenicity may be different from that of gluten.