Genetically transforming human mesenchymal stem cells to sarcomas

Nan Li, Rui Yang, Wendong Zhang, Howard D. Dorfman, Pulivarthi H. Rao, Richard Görlick

Cancer · 2009 · 66 citations · 27 references

DOIFull text

Open access

Abstract

Multilineage differentiation potential was retained during tumorigenesis of hMSCs and distinct sarcoma cell lines could arise with the same genetic events, providing good models in better understanding the concept of hMSC and in further investigation of the relationship of hMSCs and osteosarcomas.

References

27