A stress response pathway in mice upregulates somatostatin level and transcription in pancreatic delta cells through Gs and β-arrestin 1

Crystal structure of the β2 adrenergic receptor–Gs protein complex

Søren G. F. Rasmussen, Brian T. DeVree, Yaozhong Zou et al. · Nature · 2011 · 3.1K citations · Full text

Life Sciences, Biochemistry, Pharmacology +12

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

Marc Montminy, Louise M. Bilezikjian · Nature · 1987 · 1.4K citations

Medicine, Endocrinology, Molecular Biology +10

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

Karen Yamamoto, G. González, William Biggs et al. · Nature · 1988 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +15

Distinct Phosphorylation Sites on the β ₂ -Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of β-Arrestin

Kelly N. Nobles, Kunhong Xiao, Seungkirl Ahn et al. · Science Signaling · 2011 · 625 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development.

Maike Sander, Annette Neubüser, Julie Kalamaras et al. · Genes & Development · 1997 · 575 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17