Concepedia

IL-7 splicing variant IL-7δ5 induces EMT and metastasis of human breast cancer cell lines MCF-7 and BT-20 through activation of PI3K/Akt pathway

Jie Yang, Zhi Zeng, Yuyu Peng, Jianhua Chen, Ling Pan, Deshun Pan

Histochemistry and Cell Biology · 2014 · 30 citations · 25 references

DOI

Concepts

References

25

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

Kimberly S. Schluns, William C. Kieper, Stephen C. Jameson et al. · Nature Immunology · 2000 · 1.6K citations

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The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines.

Sylvia Grille, Alfonso Bellacosa, John J. Upson et al. · PubMed · 2003 · 617 citations

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Activation of NF-κB by Akt upregulates Snail expression and induces epithelium mesenchyme transition

Sylvia Julien, Isabel Puig, Elena Caretti et al. · Oncogene · 2007 · 480 citations

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IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival

Jessica A. Wofford, Heather L. Wieman, Sarah R. Jacobs et al. · Blood · 2007 · 412 citations · Full text

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Activation of PI3K Is Indispensable for Interleukin 7–mediated Viability, Proliferation, Glucose Use, and Growth of T Cell Acute Lymphoblastic Leukemia Cells

João T. Barata, Ana Silva, Joana G. Brandão et al. · The Journal of Experimental Medicine · 2004 · 274 citations · Full text

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