Concepedia

Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells

Hein te Riele, Els Robanus Maandag, Alan R. Clarke, Martin Hooper, Anton Berns

Nature · 1990 · 242 citations · 14 references

DOI

Concepts

References

14

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

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HPRT-deficient (Lesch–Nyhan) mouse embryos derived from germline colonization by cultured cells

Martin Hooper, Kate Hardy, Alan H. Handyside et al. · Nature · 1987 · 1.2K citations

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At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells

Marilyn Kozak · Journal of Molecular Biology · 1987 · 1.2K citations

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Plasmid-encoded hygromycin B resistance: the sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae

Linda Gritz, Julian Davies · Gene · 1983 · 813 citations

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Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

Maarten van Lohuizen, Sjef Verbeek, Paul Krimpenfort et al. · Cell · 1989 · 497 citations

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