Concepedia

Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice

Julio Pozueta, Roger Lefort, Elena M. Ribé, Carol M. Troy, Ottavio Arancio, Michael L. Shelanski

Nature Communications · 2013 · 102 citations · 54 references

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References

54

High-Level Neuronal Expression of Aβ<sub>1–42</sub>in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

Lennart Mucke, Eliezer Masliah, Gui-Qiu Yu et al. · Journal of Neuroscience · 2000 · 1.9K citations · Full text

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RETRACTED ARTICLE: APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

Anatoly Nikolaev, Todd McLaughlin, Dennis D.M. O’Leary et al. · Nature · 2009 · 983 citations

, , +17

Defects in regulation of apoptosis in caspase-2-deficient mice

L Bergeron, Gloria I. Perez, G. MacDonald et al. · Genes & Development · 1998 · 682 citations · Full text

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Early Aβ accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

Martin Ingelsson, Hiroaki Fukumoto, Kathy L. Newell et al. · Neurology · 2004 · 654 citations

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Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

Marcello D’Amelio, Virve Cavallucci, Silvia Middei et al. · Nature Neuroscience · 2010 · 568 citations · Full text

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