Genome-scale reconstruction of a metabolic network for Gluconobacter oxydans 621H

What is flux balance analysis?

Jeffrey D. Orth, Ines Thiele, Bernhard Ø. Palsson · Nature Biotechnology · 2010 · 4.1K citations

Natural Sciences, Earth Sciences, Physics +10

From genomics to chemical genomics: new developments in KEGG

Minoru Kanehisa · Nucleic Acids Research · 2005 · 3.2K citations · Full text

Life Sciences, Bioinformatics, Systems Biology +17

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

Jan Schellenberger, Richard Que, Ronan M. T. Fleming et al. · Nature Protocols · 2011 · 1.9K citations · Full text

Life Sciences, Bioinformatics, Systems Biology +17

A protocol for generating a high-quality genome-scale metabolic reconstruction

Ines Thiele, Bernhard Ø. Palsson · Nature Protocols · 2010 · 1.9K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +11

A genome‐scale metabolic reconstruction for Escherichia coli K‐12 MG1655 that accounts for 1260 ORFs and thermodynamic information

Adam M. Feist, Christopher S. Henry, Jennifer L. Reed et al. · Molecular Systems Biology · 2007 · 1.4K citations · Full text

Life Sciences, Microbiology, Molecular Biology +13