Concepedia

Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis

María C. de Andrés, Kei Imagawa, Ko Hashimoto, Antonio González, Mary B. Goldring, Helmtrud I. Roach, Richard O. C. Oreffo

Biochemical and Biophysical Research Communications · 2011 · 73 citations · 25 references

DOIFull text

Open access

Concepts

References

25

The role of cytokines in osteoarthritis pathophysiology

Julio Fernandes, Johanne Martel‐Pelletier, Jean‐Pierre Pelletier · Biorheology · 2002 · 1K citations

, , +17

SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity

Hirohide Yoshikawa, Kenichi Matsubara, Geng-Sun Qian et al. · Nature Genetics · 2001 · 736 citations

, , +10

The JAK‐binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

Hideo Yasukawa · The EMBO Journal · 1999 · 722 citations · Full text

, , +10

Association between the abnormal expression of matrix‐degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions

Helmtrud I. Roach, Norikazu Yamada, Kelvin Sin Chi Cheung et al. · Arthritis & Rheumatism · 2005 · 350 citations

, , +16

Evolution of the Androgen Receptor Pathway during Progression of Prostate Cancer

Peter J.M. Hendriksen, Natasja F. Dits, Koichi Kokame et al. · Cancer Research · 2006 · 230 citations

, , +11