Hirohide Yoshikawa

SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity

Hirohide Yoshikawa, Kenichi Matsubara, Geng-Sun Qian et al. · Nature Genetics · 2001 · 732 citations

Signaling Pathway, Hepatology, Human Hepatocellular Carcinoma +12

Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma

Yasuharu Niwa, Hiroaki Kanda, Yuko Shikauchi et al. · Oncogene · 2005 · 340 citations

Socs-3 Promotes, Signal Transduction, Signaling Pathway +12

SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

Oliver Galm, Hirohide Yoshikawa, Manel Esteller et al. · Blood · 2003 · 306 citations

Mutational analysis of p73 and p53 in human cancer cell lines

Hirohide Yoshikawa, Makoto Nagashima, Mary G. McMenamin et al. · Oncogene · 1999 · 62 citations

Mutational Analysis, Somatic Variant, Tumor Heterogeneity +8

SALL3 Interacts with DNMT3A and Shows the Ability To Inhibit CpG Island Methylation in Hepatocellular Carcinoma

Yuko Shikauchi, Akio Saiura, Takahiko Kubo et al. · Molecular and Cellular Biology · 2009 · 58 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +18