Concepedia

Norcantharidin enhances ABT-737-induced apoptosis in hepatocellular carcinoma cells by transcriptional repression of Mcl-1

Shuijun Zhang, Gongquan Li, Xiu-Xian Ma, Yu Wang, Guangzhi Liu, Liushun Feng, Yongfu Zhao, Gong Zhang, Yang Wu, Xuexiang Ye,

Cellular Signalling · 2012 · 69 citations · 34 references

DOI

Concepts

References

34

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Michael C. Wei, Wei‐Xing Zong, Emily H. Cheng et al. · Science · 2001 · 3.9K citations · Full text

, , +17

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

Tilman Oltersdorf, Steven W. Elmore, Alexander R. Shoemaker et al. · Nature · 2005 · 3.4K citations

, , +14

CLINICAL CANCER RESEARCH

D. W. Smithers · The Lancet · 1956 · 1.8K citations

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

Mark F. van Delft, Andrew H. Wei, Kylie D. Mason et al. · Cancer Cell · 2006 · 1.2K citations · Full text

, , +10

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

Marina Konopleva, Rooha Contractor, Twee Tsao et al. · Cancer Cell · 2006 · 1K citations · Full text

, , +16