Proceedings of the National Academy of Sciences · 1975 · 48 citations · 21 references
Life SciencesBiochemistryMolecular BiologyProtein TranslationProtein SynthesisRibosomal Rna ProcessingRibosome BiogenesisRibosome FunctionTranslation In ProkaryotesTranslational RegulationAntibiotic Inhibition Of TranslationDeacylated Transfer Rna ReleasePeptide Release MechanismRibosomal CatalysisRibosomal Protein BiosynthesisRibosomal Protein SynthesisRibosomal TranslocationRibosomally Synthesized Peptide Biosynthesis
Erythromycin A released peptidyl-tRNA in the in vitro polypeptide synthesis system with bacterial components programmed by synthetic polynucleotide. This is consistent with our hypothesis that erythromycin A inhibits translocation by preventing proper situation of oligopeptidyl-tRNA in the donor (D) site on ribosomes.
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The action of trypsin on polylysine
S G Waley, J. Watson · Biochemical Journal · 1953 · 361 citations · Full text
Hans Kössel, Uttam L. RajBhandary · Journal of Molecular Biology · 1968 · 125 citations