Concepedia

A novel Chk inhibitor, XL-844, increases human cancer cell radiosensitivity through promotion of mitotic catastrophe

Oliver Riesterer, Fumihiko Matsumoto, Li Wang, Jessica Pickett, David Molkentine, Uma Giri, Luka Milas, Uma Raju

Investigational New Drugs · 2009 · 50 citations · 32 references

DOI

Concepts

References

32

Dynamic instability of microtubule growth

Tim Mitchison, Marc W. Kirschner · Nature · 1984 · 3.3K citations

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Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

Christine E. Canman, Dae‐Sik Lim, Karlene A. Cimprich et al. · Science · 1998 · 2K citations

, , +14

Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage

Sharon Banin, Lilach Moyal, Sheau-Yann Shieh et al. · Science · 1998 · 1.8K citations

Linkage of ATM to Cell Cycle Regulation by the Chk2 Protein Kinase

Satomi Matsuoka · 1998 · 1.3K citations

Radiosensitivity in ataxia-telangiectasia: a new explanation.

Robert B. Painter, B.R. Young · Proceedings of the National Academy of Sciences · 1980 · 789 citations · Full text

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