Concepedia

Progranulin is required for proper ER stress response and inhibits ER stress-mediated apoptosis through TNFR2

Mei-Ling Li, Yanna Liu, Fei Xia, Zhimeng Wu, Li Deng, Rong Jiang, Fengjin Guo

Cellular Signalling · 2014 · 49 citations · 42 references

DOI

Concepts

References

42

XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Hiderou Yoshida, Toshie Matsui, Akira Yamamoto et al. · Cell · 2001 · 4.1K citations · Full text

, , +13

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

Matt Baker, Ian R. Mackenzie, Stuart Pickering‐Brown et al. · Nature · 2006 · 2.1K citations

, , +12

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

Ann–Hwee Lee, Neal N. Iwakoshi, Laurie H. Glimcher · Molecular and Cellular Biology · 2003 · 2.1K citations · Full text

, , +13

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

Marc Cruts, Ilse Gijselinck, Julie van der Zee et al. · Nature · 2006 · 1.5K citations

, , +11

Compromised Function of Regulatory T Cells in Rheumatoid Arthritis and Reversal by Anti-TNFα Therapy

Michael R. Ehrenstein, J. Grimley Evans, Animesh Singh et al. · The Journal of Experimental Medicine · 2004 · 1.2K citations · Full text

, , +16