A DNA vaccine expressing CFP21 and MPT64 fusion protein enhances BCG-induced protective immunity against Mycobacterium tuberculosis infection in mice

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

Robert M. Horton, Henry D. Hunt, Steffan N. Ho et al. · Gene · 1989 · 3.1K citations

Life Sciences, Genetics, Molecular Biology +10

Efficacy of BCG Vaccine in the Prevention of Tuberculosis

Graham A. Colditz · JAMA · 1994 · 1.9K citations

Veterinary Medicine, Infectious Diseases, Preventive Medicine +17

Comparative Genomics of BCG Vaccines by Whole-Genome DNA Microarray

Marcel A. Behr, Michael A. Wilson, Wendy Gill et al. · Science · 1999 · 1.5K citations

Life Sciences, Genetics, Microbiology +15

The primary mechanism of attenuation of bacillus Calmette–Guérin is a loss of secreted lytic function required for invasion of lung interstitial tissue

Tsungda Hsu, Suzie Hingley‐Wilson, Bing Chen et al. · Proceedings of the National Academy of Sciences · 2003 · 739 citations · Full text

Veterinary Medicine, Infectious Diseases, Microbiology +12

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

Alexander S. Pym, Priscille Brodin, Laleh Majlessi et al. · Nature Medicine · 2003 · 647 citations · Full text

Public Health, Immunology, Infectious Diseases +5