Concepedia

Beneficial effects of rolipram in the R6/2 mouse model of Huntington's disease

Zena DeMarch, Carmela Giampà, Stefano Patassini, Giorgio Bernardi, Francesca R. Fusco

Neurobiology of Disease · 2008 · 116 citations · 52 references

DOIFull text

Open access

Concepts

References

52

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald · Cell · 1993 · 8.4K citations · Full text

, , +13

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

, , +17

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase et al. · Science · 1997 · 2.9K citations

, , +16

Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

Stephen W. Davies, Mark Turmaine, Barbara A. Cozens et al. · Cell · 1997 · 2.2K citations · Full text

, , +17

Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease

Chiara Zuccato, Andrea Ciammola, Dorotea Rigamonti et al. · Science · 2001 · 1.3K citations

, , +17