Advances in flux balance analysis

Analysis of optimality in natural and perturbed metabolic networks

Daniel Segrè, Dennis Vitkup, George M. Church · Proceedings of the National Academy of Sciences · 2002 · 1.4K citations

Life Sciences, Biochemistry, Biology +15

Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110

Amit Varma, Bernhard Ø. Palsson · Applied and Environmental Microbiology · 1994 · 1.1K citations · Full text

Life Sciences, Microbiology, Physiology +16

Genome-Scale Reconstruction of the <i>Saccharomyces cerevisiae</i> Metabolic Network

Jochen Förster, Iman Famili, Patrick Fu et al. · Genome Research · 2003 · 1.1K citations · Full text

Life Sciences, Bioinformatics, Biology +16

Dynamic Flux Balance Analysis of Diauxic Growth in Escherichia coli

Radhakrishnan Mahadevan, Jeremy S. Edwards, Francis J. Doyle · Biophysical Journal · 2002 · 963 citations · Full text

Life Sciences, Microbiology, Bacteriology +15

In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data

Jeremy S. Edwards, Rafael U. Ibarra, Bernhard Ø. Palsson · Nature Biotechnology · 2001 · 952 citations

Life Sciences, Bioinformatics, Microbiology +14