Concepedia

Micro-CT Based Experimental Liver Imaging Using a Nanoparticulate Contrast Agent: A Longitudinal Study in Mice

Hanne Boll, Stefanie Nittka, Fabian Doyon, Michael Neumaier, Alexander Marx, Martin Kramer, Christoph Groden, Marc A. Brockmann

PLoS ONE · 2011 · 94 citations · 21 references

DOIFull text

Open access

Abstract

The nanoparticulate contrast agents ExiTron nano 6000 and 12000 provide strong contrast of the liver, spleen, lymph nodes and adrenal glands up to weeks, hereby allowing longitudinal monitoring of pathological processes of these organs in small animals, with ExiTron nano 12000 being particularly optimized for angiography due to its very high initial vessel contrast.

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