Distinct subsets of patients with systemic juvenile idiopathic arthritis based on their cytokine profiles

International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001.

Ross E. Petty, T. R. E. Southwood, Prudence Manners et al. · PubMed · 2004 · 4.2K citations · Full text

Medicine, Clinical Sciences, Pediatric Rheumatology +9

Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial

Shumpei Yokota, Tomoyuki Imagawa, Masaaki Mori et al. · The Lancet · 2008 · 797 citations

Medicine, Clinical Sciences, Pharmacotherapy +8

The pattern of response to anti–interleukin‐1 treatment distinguishes two subsets of patients with systemic‐onset juvenile idiopathic arthritis

Marco Gattorno, Alessandra Piccini, Denise Lasigliè et al. · Arthritis & Rheumatism · 2008 · 380 citations

Life Sciences, Immunology, Pharmacotherapy +16

Correlation of Serum Interleukin‐6 Levels with Joint Involvement and Thrombocytosis in Systemic Juvenile Rheumatoid Arthritis

Fabrizio De Benedetti, Margherita Massa, Piera Robbioni et al. · Arthritis & Rheumatism · 1991 · 362 citations

Life Sciences, Clinical Sciences, Immunology +12

Blood and synovial fluid cytokine signatures in patients with juvenile idiopathic arthritis: a cross-sectional study

Wilco de Jager, Esther P A H Hoppenreijs, Nico Wulffraat et al. · Annals of the Rheumatic Diseases · 2006 · 346 citations · Full text

Medicine, Clinical Sciences, Immunology +17