Solid-phase synthesis of H-Phe-Tyr-(pATAT)-NH<sub>2</sub>: a nucleopeptide fragment from the nucleoprotein of bacteriophage øX174

C.M. Dreef-Tromp, E. M. A. van Dam, Hans van den Elst, G. A. VAN DER MAREL, Jacques H. van Boom

Nucleic Acids Research · 1990 · 34 citations · 8 references

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Abstract

The preparation of the nucleopeptide H-Phe-Tyr-(pATAT)-NH2 could be realized via a solid phase phosphitetriester approach and by using the protected protecting group 2-(tert-butyldiphenylsilyoxymethyl)-benzoyl for the masking of the N6-amino function of deoxyadenosine. The latter protecting group can be removed under mild conditions with fluoride ion.

References

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