Necessity of interleukin-1β converting enzyme cascade in taxotere-initiated death signaling

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

Life Sciences, Cell Biology, Apoptosis +14

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature · 1995 · 4K citations

Life Sciences, Cell Biology, Molecular Biology +13

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

Cell · 1993 · 2.5K citations · Full text

Life Sciences, Genetics, Molecular Biology +10

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

Masahiko Miura · Cell · 1993 · 1.4K citations

Life Sciences, Cell Biology, Molecular Biology +13

CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme.

Teresa Fernandes‐Alnemri, Gerald Litwack, Emad S. Alnemri · Journal of Biological Chemistry · 1994 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13